Daniela Salvemini Selected Research

Superoxides (Superoxide)

12/2016	Nitroxidative Signaling Mechanisms in Pathological Pain.
12/2014	A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
7/2013	Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance.
5/2012	Anti-superoxide and anti-peroxynitrite strategies in pain suppression.
1/2012	Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain.
9/2011	Roles of reactive oxygen and nitrogen species in pain.
6/2011	Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.
10/2010	Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance.
4/2010	Targeting peroxynitrite driven nitroxidative stress with synzymes: A novel therapeutic approach in chronic pain management.
1/2009	Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.

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Daniela Salvemini Research Topics

Disease

53	Pain (Aches) 01/2022 - 06/2004
36	Neuralgia (Stump Neuralgia) 11/2022 - 12/2011
32	Hyperalgesia 11/2022 - 06/2004
23	Chronic Pain 10/2021 - 11/2007
19	Inflammation (Inflammations) 01/2020 - 05/2002
12	Neoplasms (Cancer) 01/2022 - 06/2003
12	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 05/2012
10	Hypersensitivity (Allergy) 11/2022 - 09/2008
9	Shock 02/2009 - 11/2002
5	Body Weight (Weight, Body) 01/2022 - 06/2003
4	Neuroinflammatory Diseases 01/2022 - 07/2013
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 05/2012
4	Multiple Sclerosis 10/2020 - 07/2014
4	Edema (Dropsy) 01/2013 - 06/2004
4	Hypotension (Low Blood Pressure) 06/2011 - 01/2003
4	Ischemia 10/2008 - 06/2002
4	Reperfusion Injury 10/2008 - 07/2002
3	Asthma (Bronchial Asthma) 01/2022 - 08/2005
3	Cognitive Dysfunction 01/2022 - 01/2018
3	Atherosclerosis 07/2019 - 07/2003
3	Wounds and Injuries (Trauma) 01/2018 - 04/2011
3	Necrosis 09/2004 - 05/2002
3	Septic Shock (Toxic Shock Syndrome) 01/2003 - 11/2002
2	Migraine Disorders (Migraine) 10/2021 - 01/2020
2	Headache (Headaches) 10/2021 - 01/2020
2	Stroke (Strokes) 11/2020 - 05/2002
2	Brain Injuries (Brain Injury) 11/2020 - 06/2003
2	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2020 - 01/2018

Drug/Important Bio-Agent (IBA)

33	Peroxynitrous Acid (Peroxynitrite)IBA 10/2021 - 06/2002
30	Superoxides (Superoxide)IBA 12/2016 - 05/2002
24	Superoxide DismutaseIBA 12/2020 - 06/2002
18	Analgesics (Analgesic Drugs)IBA 01/2022 - 11/2007
16	Purinergic P1 Receptors (Adenosine Receptor)IBA 07/2021 - 05/2012
15	Opioid Analgesics (Opioids)IBA 01/2022 - 08/2012
15	EnzymesIBA 01/2020 - 06/2002
13	Morphine (MS Contin)FDA LinkGeneric 10/2020 - 04/2009
12	CeramidesIBA 09/2017 - 02/2008
11	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2020 - 06/2002
11	imisopasem manganeseIBA 05/2008 - 05/2002
10	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2021 - 06/2002
10	Pharmaceutical PreparationsIBA 10/2021 - 07/2010
10	Adenosine (Adenocard)FDA LinkGeneric 01/2021 - 01/2003
10	CarrageenanIBA 01/2020 - 06/2004
10	CytokinesIBA 01/2019 - 01/2003
10	Opiate AlkaloidsIBA 07/2013 - 11/2007
9	Sphingosine-1-Phosphate ReceptorsIBA 11/2022 - 03/2011
9	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 11/2020 - 03/2011
8	Fingolimod Hydrochloride (FTY720)FDA Link 11/2020 - 01/2013
7	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 05/2012
7	Paclitaxel (Taxol)FDA LinkGeneric 09/2021 - 05/2012
7	Narcotics (Narcotic Analgesics)IBA 07/2021 - 06/2004
7	SphingolipidsIBA 11/2020 - 08/2011
7	3-nitrotyrosineIBA 08/2012 - 08/2002
6	N(6)- (3- iodobenzyl)- 5'- N- methylcarboxamidoadenosineIBA 07/2021 - 05/2012
6	PorphyrinsIBA 12/2020 - 04/2010
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021 - 05/2002
5	ProstaglandinsIBA 12/2020 - 02/2008
5	AntioxidantsIBA 12/2020 - 05/2004
5	MRS5698IBA 01/2020 - 12/2014
5	AnionsIBA 01/2015 - 05/2002
5	M40401IBA 10/2004 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 09/2021 - 01/2013
4	Interleukin-10 (Interleukin 10)IBA 01/2021 - 02/2015
4	Bortezomib (Velcade)FDA Link 01/2020 - 05/2012
4	Oxygen (Dioxygen)IBA 12/2016 - 01/2003
4	NADPH Oxidases (NAD(P)H oxidase)IBA 12/2014 - 07/2003
4	Oxidants (Oxidizing Agents)IBA 08/2012 - 06/2002
3	Adenosine KinaseIBA 11/2022 - 01/2015
3	NLR ProteinsIBA 11/2022 - 01/2020
3	Therapeutic UsesIBA 01/2022 - 05/2004
3	Free RadicalsIBA 09/2021 - 06/2003
3	LigandsIBA 07/2021 - 06/2004
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 12/2020 - 06/2004
3	Adenosine A3 ReceptorIBA 11/2020 - 01/2015
3	OvalbuminIBA 10/2020 - 08/2005
3	Purinergic P1 Receptor AgonistsIBA 01/2017 - 12/2014
3	NitrogenIBA 12/2016 - 10/2010
3	N-Methylaspartate (NMDA)IBA 01/2013 - 05/2002
3	Interleukin-2 (IL2)IBA 06/2011 - 06/2003
3	dihydroceramide desaturaseIBA 02/2009 - 02/2008
3	Ligases (Synthetase)IBA 11/2002 - 06/2002
2	InflammasomesIBA 11/2022 - 11/2020
2	SEW2871IBA 11/2022 - 01/2013
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 01/2003
2	ProdrugsIBA 01/2022 - 01/2020
2	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 09/2021 - 01/2013
2	Peptides (Polypeptides)IBA 01/2021 - 11/2020
2	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 12/2014
2	manganese(III)-tetrakis(4-benzoic acid)porphyrinIBA 12/2020 - 01/2009
2	Reactive Nitrogen SpeciesIBA 12/2020 - 11/2016
2	Dinoprostone (PGE2)FDA Link 12/2020 - 08/2011
2	Sirtuin 3IBA 11/2020 - 01/2020
2	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 11/2020 - 01/2019
2	AcidsIBA 06/2020 - 04/2010
2	Naloxone (Narcan)FDA LinkGeneric 01/2020 - 08/2012

Therapy/Procedure

23	Therapeutics 01/2022 - 05/2004
15	Drug Therapy (Chemotherapy) 01/2022 - 05/2012
3	Intraperitoneal Injections 11/2020 - 09/2004
3	Analgesia 12/2016 - 09/2008
2	Spinal Injections 11/2020 - 01/2013